May 29th, 2010
On some interesting news I read a few months ago, Pfizer’s (a major pharmaceutical company) patent on its impotence drug Viagra has been partially rejected after the U.S. Patent and Trademark Office (USPTO) said it wasn’t different enough from a Chinese herb called yin yang huo (more popularly known as Horny Goat Weed).

Yin Yang Huo (Horny Goat Weed)
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Tags: Bayer, Cardioquin, Cephaelis, Cialis, Cinchona, Crystodigin, Digitalis, Dr. Christine Daniel, dysentery, Eli Lilly, Eli Lilly and Company, erectile dysfunction, FDA, Foxglove, heart conditions, horny goat weed, icariin, Ipecacuanha, Lanoxin, Levitra, malaria, Pfizer, pharmaceutical, Plasmodium falciparum, Quin-Release, Quinaglute Dura-tabs, Quinidex Extentabs, Quinine, United States Patent and Trademark Office, USPTO, Viagra, yin yang huo
Posted in BioTech/Pharma | No Comments »
May 13th, 2010
Today at the “Bay Area JUG Roundup 2010″ at Oracle’s office in Redwood City, I got my first glimpse into what the future of Java may be under Oracle. It was a fun event and a good sign that Oracle is heading in the right direction with its approach to Java. Read the rest of this entry »
Tags: Bay Area JUG Roundup 2010, IBM, James Gosling, Java, JUG, Oracle, Sun, Sun Microsystems, Tiobe Index
Posted in Bay Area JUG Roundup 2010 | 1 Comment »
March 30th, 2010

Charles Darwin
Last month I attended the “9th Annual Evolutionpalooza! – Darwin Day in San Francisco.” The event was at the main branch of the San Francisco Public Library. The short presentation by NASA Astrobiologist Dr. Lynn Rothschild on Darwin and some of his achievements as well as her brief intro on Astrobiology was interesting. Most of the information presented was nothing ground-breaking to those who are avid readers or dedicated scientists/researchers; however, I find it always good to hear information from different perspectives for discussion purposes and for refreshing one’s memory. One of the reasons I love the Bay Area so much is that there are many intellects in the area that are willing to organize events like this and participate regularly in regards to intellectual conversation. Also, the location was ideal as many library attendees who otherwise may never take interest in such a subject had an opportunity to attend and engage.
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Tags: 9th Annual Evolutionpalooza, Albert Einstein, atheist, Charles Darwin, Darwin Day, Genesis, God, hominids, Lynn Rothschild, religion, Stephen Hawking, The Origin of Species
Posted in Biology | 1 Comment »
March 30th, 2010

Urea - a molecular compound in human urine

Friedrick Wohler
In the past, organic compounds were restricted to those that could be produced only from living entities. These compounds were thought to contain a “vital force” based on their natural origin. This “vital force” concept was disproved in 1828 by a Geman chemist, Friedrick Wohler. Wohler synthesized a molecular compound found in human urine called urea. To accomplish this task he used the molecular compounds ammonia and cyanic acid. Urea became the first organic molecule synthesized by a chemist.
Tags: Friedrick Wohler, human urine, organic compound, organic molecule, urea
Posted in Interesting Facts | No Comments »
February 14th, 2010
We can learn a lot from the world of parasites, which in general also includes bacteria, viruses and fungi. The medical profession has long focused on bacteria and viruses more-so than parasitic protozoa partly due to the fact of how causes of disease have traditionally been identified. A pathogen had to be shown to be associated with a particular disease. In this respect it had to be isolated, grown in a pure culture, and inoculated into a host which would then produce the disease. The organism in the host also had to be shown to be the pathogen that the host was inoculated with. Bacteria and viruses were easily characterized as disease causing agents within these set of rules, but protozoa, despite their ability to cause severe disease, never really fell easily into this category. Protozoa have an extremely complex process not only in terms of the biological sense but also in terms of survival and the means in which they infect their hosts. Read the rest of this entry »
Tags: Ancylostoma duodenale. Necator americanus, blood thinner, Corvas International, herpes virus, hookworm, HSV, inflammation, Louisiana State University School of Veterinary Medicine, MediGene, Myxoma virus, oncolytic viruses, parasites, protozoa, storke, Viron Therapeutics, VT-111
Posted in BioTech/Pharma, Business | 2 Comments »
December 20th, 2009

Sufferers of sleeping sickness
Imagine living day to day in a place plagued by constant poverty and unimaginable disease. AIDS, African trypanosomiasis (sleeping sickness), dracunculiasis (guinea worm disease), malaria, nodding syndrome, and onchocerciasis (river blindness) are some of the most common diseases the people of southern Sudan have to live in constant fear of. Although some of the diseases widespread in southern Sudan such as AIDS and malaria are also found elsewhere, southern Sudan is also plagued by some of the more exotic diseases such as guinea worm disease, nodding syndrome, river blindness, and sleeping sickness that are almost entirely local to Sudan and neighboring African countries.
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Tags: African trypanosomiasis, AIDS, Ascaris lumbricoides, dracunculiasis, Ebola, Eflornithine, guinea worm disease, hookworm, malaria, Melarsoprol, nodding syndrome, onchocerciasis, parasites, Pentamidine, river blindness, roundworm, sleeping sickness, Sudan, Suramin, The Bill and Melinda Gates Foundation, The Carter Center, Trypanosoma brucei, trypanosome, whipworm
Posted in BioTech/Pharma | 1 Comment »
November 1st, 2009
European Americans are ten to forty times more likely than African Americans to get a very aggressive type of skin cancer called Melanoma. People of Asian descent are more likely to have the inability to process alcohol efficiently – exposing them to more toxicity. People of Northern European descent have a predisposition for Type 1 diabetes. High blood pressure is twice as common in African Americans than in the rest of the American population. Native Americans have higher rates of tuberculosis, pneumonia, and influenza. I’ll stop there; the list is rather large.
I mention the above statistics to bring the point home for the need for more targeted or “personalized” drugs within the Pharma industry. A “one size fit all” approach for every disease/disorder simply does not aim for maximum effectiveness. Clearly the above example and more importantly common sense points to the fact that every human being is not like every other human being when it comes to appropriate medical treatment and disease prevention. Individuals have different germlines based on many factors within the evolutionary track of a specific population. Read the rest of this entry »
Tags: BiDil, Biotech, NitroMed, Personalized Medicine, Pharma, Pharmaceuticals, Pharmacogenetics, Targeted Medicine
Posted in BioTech/Pharma, Business | 1 Comment »
September 23rd, 2009
I just finished up my last class to get the UC Berkeley Java Certificate. The program is offered by UC Berkeley Extension, an arm of UC Berkeley. The program consists of taking and passing three Java programming courses spanning 90 hours of instruction by seasoned professionals. It’s a great way to keep your skills up-to-date, expand your skills, and network with others. However, it is a bit expensive at around $700 – $800 a class + books.
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Tags: J2EE, Java, Oracle, Sun Microsystems, UC Berkeley, UC Berkeley Extension, UC Berkeley Java Certificate
Posted in Java | 1 Comment »
June 22nd, 2009
In April of 2009, Pfizer agreed to buyout Wyeth for $68 billion; Pfizer’s market cap at that time was just around $100 billion. The following month Merck trumped the Pfizer deal with a $41 billion merger with Schering-Plough. What was Merck’s market cap at the time? – Roughly around $50 billion. Not to be outdone, Roche rounded-up the mega-mergers of 2009 (so far) with a $46.8 billion deal to acquire Genentech. However, it must be mentioned that Roche already had a majority stake in Genentech (55.8%), so we’re really talking about $46.8 billion for the remaining 44.2 % of Genentech it did not already own. Read the rest of this entry »
Tags: Biotech, Cozaar, Genentech, Lipitor, Mega-Mergers, Merck, Pfizer, Pharma, Pharmaceuticial, Roche, Schering-Plough, Singulair, Wall Street
Posted in BioTech/Pharma, Business | No Comments »
April 9th, 2009
At a Google Technology User Group meet-up last night, I listened to a presentation by a Google App Engine Engineer, Jeff Scudder. This past Sunday night Google announced the support for Java on there App Engine service. Previously, the only language that was supported was Python. Also, there is now integration with Google Web Toolkit, and a Google Plugin for Eclipse.
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Tags: Buddypoke, Eclipse Plug-in, Google App Engine, Google Web Toolkit, GWT, Java, Silicon Valley Google Technology User Group
Posted in Development Tools, Google App Engine, Technology | 1 Comment »